Aspergillus tubingensis S23 as a promising source of pharmaceutically important secondary metabolites
Aspergillus tubingensis S23 как перспективный источник фармацевтически значимых вторичных метаболитов | Aspergillus tubingensis S23 farmatsevtik ahamiyatga ega ikkilamchi metabolitlarning istiqbolli manbai sifatida
Partner conferences of the International Scientific Journal Research Focus, 1(8), 285–288
Аннотация
The biosynthetic potential of Aspergillus tubingensis S23, an endophytic fungus isolated from the medicinal plant Eremostachys isochila, was evaluated through whole-genome sequencing and comparative genome mining. Molecular phylogeny and phylogenomics supported its identification as A. tubingensis. antiSMASH predicted 95 biosynthetic gene cluster (BGC) regions, including regions similar to characterized clusters associated with kojic acid, yanuthone D, clavaric acid, TAN-1612, nidulanin A, and burnettiene A. These results indicate substantial potential for genome-guided natural-product discovery, although the production and biological activities of the predicted compounds require experimental verification.
Ключевые слова
Aspergillus tubingensisendophytic fungisecondary metabolitesbiosynthetic gene clusterskojic acidnatural-product discovery
Как цитировать
Kholikova Mavjuda Jonizokovna; Khan Asifullah; Eshboev Farhod Bakir ugli (2026). Aspergillus tubingensis S23 as a promising source of pharmaceutically important secondary metabolites. Partner conferences of the International Scientific Journal Research Focus, 1(8), 285–288. https://doi.org/10.66073/ReFocus-Conf/3010082
- Идентификатор
- https://rf-library.uz/article/0adfdf92f0f8/aspergillus-tubingensis-s23-as-a-promising-source-of-pharmaceutically-important
- DOI
- 10.66073/ReFocus-Conf/3010082
- Лицензия
- Copyright (c) 2026 Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan; Authors
- Издатель
- LLC Ilm-fan va innovatsiyalar akademiyasi
- Добавлено в репозиторий
- 2026-11-03
