Aspergillus tubingensis S23 as a promising source of pharmaceutically important secondary metabolites

Kholikova Mavjuda Jonizokovna; Khan Asifullah; Eshboev Farhod Bakir ugli

doi:10.66073/ReFocus-Conf/3010082

ARTICLE 2026 Vol 1 · No 8 EN 0adfdf92f0f8

Aspergillus tubingensis S23 as a promising source of pharmaceutically important secondary metabolites

Aspergillus tubingensis S23 как перспективный источник фармацевтически значимых вторичных метаболитов | Aspergillus tubingensis S23 farmatsevtik ahamiyatga ega ikkilamchi metabolitlarning istiqbolli manbai sifatida

Kholikova Mavjuda Jonizokovna National University of Uzbekistan named after Mirzo Ulugbek
Khan Asifullah Institute for Advanced Studies at New Uzbekistan University
Eshboev Farhod Bakir ugli Institute for Advanced Studies at New Uzbekistan University

Partner conferences of the International Scientific Journal Research Focus, 1(8), 285–288

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Abstract

The biosynthetic potential of Aspergillus tubingensis S23, an endophytic fungus isolated from the medicinal plant Eremostachys isochila, was evaluated through whole-genome sequencing and comparative genome mining. Molecular phylogeny and phylogenomics supported its identification as A. tubingensis. antiSMASH predicted 95 biosynthetic gene cluster (BGC) regions, including regions similar to characterized clusters associated with kojic acid, yanuthone D, clavaric acid, TAN-1612, nidulanin A, and burnettiene A. These results indicate substantial potential for genome-guided natural-product discovery, although the production and biological activities of the predicted compounds require experimental verification.

Keywords

Aspergillus tubingensis endophytic fungi secondary metabolites biosynthetic gene clusters kojic acid natural-product discovery

How to cite

Kholikova Mavjuda Jonizokovna; Khan Asifullah; Eshboev Farhod Bakir ugli (2026). Aspergillus tubingensis S23 as a promising source of pharmaceutically important secondary metabolites. Partner conferences of the International Scientific Journal Research Focus, 1(8), 285–288. https://doi.org/10.66073/ReFocus-Conf/3010082

Identifier: https://rf-library.uz/article/0adfdf92f0f8/aspergillus-tubingensis-s23-as-a-promising-source-of-pharmaceutically-important
DOI: 10.66073/ReFocus-Conf/3010082
Licence: Copyright (c) 2026 Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan; Authors
Publisher: LLC Ilm-fan va innovatsiyalar akademiyasi
Added to repository: 2026-11-03