Antimicrobial screening and molecular identification of active endophytic bacterial isolates from Ferula varia

Murodullayev Dilmurod Dilshodovich; Alimova Dildora Farkhod kizi; Temirova Marguba; Rayimberdiyeva Sanobar; Absattorova Khursanoy; Rustamova Nigora

doi:10.66073/ReFocus-Conf/3010016

ARTICLE 2026 Vol 1 · No 8 EN e7532658d637

Antimicrobial screening and molecular identification of active endophytic bacterial isolates from Ferula varia

Антимикробный скрининг и молекулярная идентификация активных эндофитных бактериальных изолятов из Ferula varia | Ferula varia o‘simligidan ajratilgan faol endofit bakteriya izolyatlarining antimikrob skriningi va molekulyar identifikatsiyasi

Murodullayev Dilmurod Dilshodovich Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Alimova Dildora Farkhod kizi Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan
Temirova Marguba Karshi State University
Rayimberdiyeva Sanobar Karshi State University
Absattorova Khursanoy Karshi State University
Rustamova Nigora Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan

Partner conferences of the International Scientific Journal Research Focus, 1(8), 74–76

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Abstract

Endophytic bacteria from medicinal plants are a promising source of antimicrobial metabolites, and this study evaluated the endophytic isolates of Ferula varia (more than 40 isolates from roots, stems, leaves, and flowers) against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, and Candida albicans. Six isolates showed antimicrobial activity and were identified by 16S rRNA gene sequencing as Bacillus pumilus, B. atrophaeus, B. rugosus, and Serratia odorifera, with the sequences deposited in NCBI GenBank. Four of these isolates (FV1i, FV3i, FVP1.1, and FVB1) were active against all five test organisms, making them promising candidates for further study of their bioactive metabolites.

Keywords

Ferula varia endophytic bacteria antimicrobial activity inhibition zone 16S rRNA gene sequencing molecular identification antimicrobial metabolites

How to cite

Murodullayev Dilmurod Dilshodovich; Alimova Dildora Farkhod kizi; Temirova Marguba; Rayimberdiyeva Sanobar; Absattorova Khursanoy; Rustamova Nigora (2026). Antimicrobial screening and molecular identification of active endophytic bacterial isolates from Ferula varia. Partner conferences of the International Scientific Journal Research Focus, 1(8), 74–76. https://doi.org/10.66073/ReFocus-Conf/3010016

Identifier: https://rf-library.uz/article/e7532658d637/antimicrobial-screening-and-molecular-identification-of-active-endophytic
DOI: 10.66073/ReFocus-Conf/3010016
Licence: Copyright (c) 2026 Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan; Authors
Publisher: LLC Ilm-fan va innovatsiyalar akademiyasi
Added to repository: 2026-11-03